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C57BL/6J-Tg(Kcnip2-cre/ERT2)NIDA099Htz/J
Cat. No.: CEMM-07250801
Common Name: Kcnip2-CreERT2
These transgenic BAC mice express tamoxifen-inducible cre-ERT2 from the mouse Kcnip2 promoter. Expression occurs in Kcnip2-expressing cells, including a subclass of inhibitory interneurons in the dorsal horn of the spinal cord.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Kcnip2-cre/ERT2)NIDA099Htz
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| Allele Name |
transgene insertion NIDA099
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| Allele Attributes |
Recombinase-expressing; Inducible
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| Gene Symbol |
Tg(Kcnip2-cre/ERT2)NIDA099Htz
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| Gene Name |
transgene insertion NIDA099
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| Chromosome |
UN
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| Expressed Genes |
cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene
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| MGI Accession ID | show more close |
| Site of Expression |
When crossed with mice carrying loxP-flanked sequences of interest, Tamoxifen inducuble Cre is expressed in Kcnip2-expressing cells, including a subclass of inhibitory interneurons in the dorsal horn of the spinal cord.
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| Strain of Origin |
C57BL/6J
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| Molecular Note |
Expression of tamoxifen-inducible Cre-ERT2 is driven from the mouse Kcnip2 promoter contained on BAC RP23-146N4. This BAC encodes 5 additional genes: Fgf8, Npm3, Mgea5, Gm6813, and partial 9130011E15Rik. The modified BAC vector was introduced to C57BL/6J embryos.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J Noncarrier
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| Breeding Considerations |
Hemizygotes are viable and fertile.
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| Breeding Strategy |
Noncarrier x Hemizygote; Hemizygote x Noncarrier
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For Research Use Only.
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