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C57BL/6-Vipr2em1Litt/J
Cat. No.: CEMM-07251014
Common Name: Vipr2fl
Exons 3 and 4 of the mouse Vipr2 (vasoactive intestinal peptide receptor 2) gene are flanked by loxP sites in these CRISPR-generated Vipr2fl mice. Cre recombinase-mediated excision of the floxed region results in a knock-out allele.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Vipr2em1Litt
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| Allele Name |
endonuclease-mediated mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Vipr2
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| Gene Name |
vasoactive intestinal peptide receptor 2
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| Chromosome |
12
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| MGI Accession ID | show more close |
| Strain of Origin |
Not Specified
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| Molecular Note |
CRISPR/Cas9 genome editing is used to introduce loxP sites on either side of the exons 3-4. Resultant mice were sequenced to identify mice homozygous for both loxP insertions.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6NJ
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| Breeding Considerations |
Heterozygous and homozygous floxed mice are viable and fertile.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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