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C57BL/6-Camk2atm1Vyb/J
Cat. No.: CEMM-07250054
Common Name: CA3 α-CaMKII KO
These floxed mutant mice possess loxP sites flanking exon 2 of the Camk2a gene. This strain may be useful for generating conditional mutations in applications related to neurological studies.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Camk2atm1Vyb
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Camk2a
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| Gene Name |
calcium/calmodulin-dependent protein kinase II alpha
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| Chromosome |
18
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6
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| Molecular Note |
A loxP site was introduced into intron 1 and an frt/loxP-flanked neo cassette was introduced to intron 2 via homologous recombination. The neo cassette was removed by transient expression of flp recombinase in correctly targeted ES cells. Resulting mutant mice carry a floxed exon 2 allele.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice are bred.
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For Research Use Only.
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