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C57BL/6-C1ql2em1(cre)Gfng/J
Cat. No.: CEMM-07251080
Common Name: C1QL2-IRES-Cre
C1ql2-Cre knock-in mice express Cre recombinase from the mouse C1ql2 (complement component 1, q subcomponent-like 2) promoter in C1ql2-expressing cells/tissues. These mice can be used to target anterior thalamic circuits, among other brain regions that also contain C1QL2‐expressing neurons, and may be useful in studies of autism, schizophrenia, and other neuropsychiatric disorders.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
C1ql2em1(cre)Gfng
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| Allele Name |
endonuclease-mediated mutation 1
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
C1ql2
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| Gene Name |
complement component 1
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| Chromosome |
1
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6NTac
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| Molecular Note |
An IRES-Cre-pA cassette was introduced immediately after the stop codon of the mouse C1ql2 gene in C57BL/6NTac embryos using CRISPR/Cas9 methodologies.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
Heterozygotes are viable and fertile.
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| Breeding Strategy |
Wild-type x Heterozygote; Heterozygote x Wild-type
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For Research Use Only.
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