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B6.Cg-Crebbptm1Jvd/J
Cat. No.: CEMM-07250558
Common Name: CBPflox
These floxed mutant mice possess loxP sites flanking exon 9 of the Crebbp gene. This strain may be useful for generating conditional mutations in applications related to transcriptional regulation, chromatin remodeling, hematopoiesis, formation of short- and long-term memory, T cell development and tumor suppression.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Crebbptm1Jvd
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Crebbp
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| Gene Name |
CREB binding protein
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| Chromosome |
16
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| MGI Accession ID | show more close |
| Strain of Origin |
Not Specified
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| Molecular Note |
A loxP recombination site was inserted in intron 8 and a floxed Neo-HSV tk selection cassette was inserted in intron 9. The selection cassette was then removed from correctly targeted ES cells by by transient expression of Cre recombinase.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygotes.
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| Breeding Strategy |
Homozygote x Homozygote
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For Research Use Only.
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