B6;C3-Oxtrem2(icre)Yinn/J

Cat. No.: CEMM-07251117

Common Name: Oxtr-T2A-iCre
Oxtr1xPA-iCre knock-in mice express a PA-tag and a codon improved cre recombinase (icre) under direction of the endogenous oxytocin receptor (Oxtr) promoter in brain regions. This mouse strain could be useful for manipulation of oxytocin receptor-expressing cells.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Oxtrem2(icre)Yinn
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Allele Name
endonuclease-mediated mutation 2
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Allele Attributes
Recombinase-expressing; Epitope tag
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Gene Symbol
Oxtr
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Gene Name
oxytocin receptor
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Chromosome
6
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MGI Accession ID show more close
Strain of Origin
(C57BL/6 x C3H)F1
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Molecular Note
Using CRISPR/Cas9 technology, a 1xPA-tag and a T2A-iCre expression cassette were inserted into the Oxtr gene just upstream of the stop codon.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
When maintaining a live colony, homozygous mice may be bred together.
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Breeding Strategy
Heterozygote x Heterozygote
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For Research Use Only.
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