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B6;C3-Oxtrem2(icre)Yinn/J
Cat. No.: CEMM-07251117
Common Name: Oxtr-T2A-iCre
Oxtr1xPA-iCre knock-in mice express a PA-tag and a codon improved cre recombinase (icre) under direction of the endogenous oxytocin receptor (Oxtr) promoter in brain regions. This mouse strain could be useful for manipulation of oxytocin receptor-expressing cells.
Inquiry
Status | Live Mouse Frozen Embryo |
Age | 4 weeks 12 weeks Customized Age |
Sex | Male Female |
GENETICS | |
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Allele Symbol |
Oxtrem2(icre)Yinn
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Allele Name |
endonuclease-mediated mutation 2
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Allele Attributes |
Recombinase-expressing; Epitope tag
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Gene Symbol |
Oxtr
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Gene Name |
oxytocin receptor
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Chromosome |
6
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MGI Accession ID | show more close |
Strain of Origin |
(C57BL/6 x C3H)F1
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Molecular Note |
Using CRISPR/Cas9 technology, a 1xPA-tag and a T2A-iCre expression cassette were inserted into the Oxtr gene just upstream of the stop codon.
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HUSBANDRY | |
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Suggested Controls |
C57BL/6J
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Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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