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B6.129(SJL)-Oxtrtm1.1Wsy/J
Cat. No.: CEMM-07250109
Common Name: Oxtrflox
Mice homozygous for the Oxtrflox targeted allele harbor loxP sites flanking exons 2-3 of the oxytocin receptor (Oxtr) gene, and may be used for spatial and temporal inactivation of the oxytocin receptor in studying parturition and lactation, as well as social, behavioral, and learning disorders such as autism and anxiety.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Oxtrtm1.1Wsy
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Oxtr
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| Gene Name |
oxytocin receptor
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| Chromosome |
6
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
Germ line, flp-mediated recombination was used to remove the neo cassette leaving exons 2 and 3 floxed. Autoradiography confirmed wild-type protein expression.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred. The donating investigator breeds heterozygotes with C57BL/6J inbred mice.
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For Research Use Only.
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