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B6.129(SJL)-Grip1tm1Rlh/J
Cat. No.: CEMM-07250538
The first PDZ domain of Grip1 is flanked by loxP sites in this conditional knockout strain. This enables the development of Cre-mediated knockouts useful in studies of synaptic plasticity.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Grip1tm1Rlh
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Grip1
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| Gene Name |
glutamate receptor interacting protein 1
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| Chromosome |
10
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| MGI Accession ID | show more close |
| Strain of Origin |
(129X1/SvJ x 129S1/Sv)F1-Kitl+
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| Molecular Note |
A loxP site was inserted upstream of the first coding exon and an FRT flanked neo cassette with a 3' loxP site was inserted downstream of this exon. Germ line, flp-mediated recombination was used to remove the neo cassette leaving the first coding exon floxed.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
Heterozygous and homozygous floxed mice are viable and fertile.
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For Research Use Only.
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