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B6.129S6(FVB)-Brs3tm1.1Rei/J
Cat. No.: CEMM-07250859
Common Name: Brs3 flox
These floxed mutant mice possess loxP sites flanking exon 2 of the X-linked Brs3 gene. This strain may be useful for generating conditional mutations in applications related to the regulation of metabolism and obesity.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Brs3tm1.1Rei
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Brs3
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| Gene Name |
bombesin-like receptor 3
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| Chromosome |
X
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| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
The targeting vector contains a loxP-flanked PGK-Neo selection cassette inserted downstream of exon 2 of the targeted gene, and another loxP site inserted upstream of exon 2. Cre-mediated recombination removed the downstream floxed neo cassette and left exon 2 floxed.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, these mice can be bred as homozygous females and hemizygous males (the gene is X linked).
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For Research Use Only.
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