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B6;129S6-Prkcgtm2(cre/ERT2)Ddg/J
Cat. No.: CEMM-07250789
Common Name: PKCγCreERT2
These knock-in/knock-out targeted mutant mice express tamoxifen-inducible cre-ERT2 fusion protein from the mouse Prkcg promoter in the spinal cord dorsal horn, hippocampus, cerebellum, and corticospinal tract.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Prkcgtm2(cre/ERT2)Ddg
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Recombinase-expressing; Inducible
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| Gene Symbol |
Prkcg
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| Gene Name |
protein kinase C
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| Chromosome |
7
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| Expressed Genes |
cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene
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| MGI Accession ID | show more close |
| Site of Expression |
Tamoxifen-inducible Cre-ERT2 fusion protein is expressed in the spinal cord dorsal horn, hippocampus, cerebellum, and corticospinal tract.
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| Strain of Origin |
129S6/SvEvTac
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| Molecular Note |
A Cre recombinase-estrogen receptor T2 (CreERT2) fusion-FRT Neomycin-FRT loxP cassette was introduced into the first coding ATG of exon 1.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6129SF2/J
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| Breeding Considerations |
Heterozygous and homozygous mice are viable and fertile.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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