B6.129(Cg)-Txnrd1tm1Ees/J

Cat. No.: CEMM-07250657

Common Name: Txnrd1cond
Txnrd1cond is a floxed allele with loxP sites flanking exons 1-2 of the thioredoxin reductase 1 gene. Removal of the floxed sequence creates a null allele. These mice may be useful in studying redox homeostasis.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Txnrd1tm1Ees
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Allele Name
targeted mutation 1
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Allele Attributes
Conditional ready (e.g. floxed); No functional change
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Gene Symbol
Txnrd1
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Gene Name
thioredoxin reductase 1
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Chromosome
10
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MGI Accession ID show more close
Strain of Origin
129X1/SvJ
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Molecular Note
LoxP sites were inserted upstream of exon 1 and in intron 2.
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HUSBANDRY
Suggested Controls
C57BL/6J
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Breeding Considerations
When maintaining a live colony, heterozygous mice may be bred together, to wildtype mice from the colony or to C57BL/6J inbred mice. Alternatively, homozygous mice may be bred together.
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For Research Use Only.
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