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B6.129(Cg)-Oprl1tm1.1Mrbr/J
Cat. No.: CEMM-07251055
Common Name: NOPRloxP/YFP
NOPRloxP/YFP conditional mutant mice possess loxP sites flanking exons 3-4 and an EYFP reporter (that expresses prior to cre recombination) in the Oprl1 (opioid receptor-like 1) gene and may be useful in generating conditional mutations to study reward motivation.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Oprl1tm1.1Mrbr
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); Reporter
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| Gene Symbol |
Oprl1
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| Gene Name |
opioid receptor-like 1
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| Chromosome |
2
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| MGI Accession ID | show more close |
| Strain of Origin |
129
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| Molecular Note |
The targeting construct is designed to contain a loxP site upstream of exon 3, an EYFP reporter fused to the 3' end of exon 4, a polyA, and an FRT flanked neomycin cassette followed by a second loxP site. Flp-mediated recombination removed the FRT flanked neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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