STOCK Adgrl1tm2.1Sud/J

Cat. No.: CEMM-07251010

Common Name: Myc-Lphn1 cKI
Myc-Lphn1 cKI mice express Myc-tagged mouse ADGRL1 (adhesion G protein-coupled receptor L1; also called LPHN1) protein. Cre recombinase-mediated excision of floxed exon 2 results in a knock-out allele.
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Status Live Mouse
Frozen Embryo
Age 4 weeks
12 weeks
Customized Age
Sex Male
Female
GENETICS
Allele Symbol
Adgrl1tm2.1Sud
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Allele Name
targeted mutation 2.1
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Allele Attributes
Conditional ready (e.g. floxed); Epitope tag
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Gene Symbol
Adgrl1
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Gene Name
adhesion G protein-coupled receptor L1
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Chromosome
8
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MGI Accession ID show more close
Strain of Origin
(C57BL/6J x 129S6/SvEvTac)F1
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Molecular Note
A FRT flanked neomycin cassette and loxP site were introduced to intron 1, a Myc tag was inserted after the signal peptide in exon 2, and loxP and FRT sites were placed in intron 2 of the gene. Flp-mediated recombination removed the FRT flanked neo cassette.
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HUSBANDRY
Suggested Controls
B6129SF2/J
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Breeding Considerations
Heterozygous and homozygous floxed mice are viable and fertile.
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Breeding Strategy
Heterozygote x Heterozygote
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For Research Use Only.
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