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STOCK Nogtm1.1Rmh/J
Cat. No.: CEMM-07250303
These floxed mutant mice possess loxP sites flanking the coding region of the noggin gene. This strain may have applications in studying bone morphogenetic protein signaling during embryonic development and in postnatal tissues.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Nogtm1.1Rmh
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Nog
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| Gene Name |
noggin
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| Chromosome |
11
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| Expressed Genes |
Nog, noggin, mouse, laboratory
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| MGI Accession ID | show more close |
| Strain of Origin |
129P2/OlaHsd
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| Molecular Note |
A loxP site was placed upstream of the coding region of the Noggin (Nog) gene, and a FRT flanked neomycin resistance (neo) cassette and a second loxP site were placed downstream. Flp-mediated recombination removed the neo cassette.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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For Research Use Only.
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