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C57BL/6-Ppp3r1tm1Stl/J
Cat. No.: CEMM-07250055
Common Name: fCNB1
These floxed mutant mice possess loxP sites flanking exons 2-4 of the Ppp3r1 gene. This strain may be useful for generating conditional mutations in applications related to neural networks in learning and memory.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Ppp3r1tm1Stl
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| Allele Name |
targeted mutation 1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Ppp3r1
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| Gene Name |
protein phosphatase 3
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| Chromosome |
11
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| MGI Accession ID | show more close |
| Strain of Origin |
B6.Cg-Thy1a
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| Molecular Note |
Homologous recombination flanked the three major coding exons, exons 2-4, with a loxP site and a LFNT cassette. The LFNT cassette consisted of PGK-neomycin and HSV-thymidine kinase selection sequences flanked by a pair of loxP sites and a pair of FRT sites. Cre- or Flp-mediated recombination in ES cells removed the PGK-neomycin and HSV-thymidine kinase sequences prior to production of chimeras.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice are bred.
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For Research Use Only.
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