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C57BL/6-Arid1bem2Hzhu/J
Cat. No.: CEMM-07250900
Common Name: Arid1b Flox (Arid1bFl; floxed exon 5)
Arid1b Flox (Arid1bFl; floxed exon 5) mice have a CRISPR/cas9-generated, Cre-conditional knock-out allele. These mice may be useful in studying the SWI/SNF chromatin-remodeling complex, autism spectrum disorder, intellectual disability, corpus callosum agenesis and Coffin-Siris syndrome.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Arid1bem2Hzhu
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| Allele Name |
endonuclease-mediated mutation 2
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| Allele Attributes |
Conditional ready (e.g. floxed)
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| Gene Symbol |
Arid1b
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| Gene Name |
AT rich interactive domain 1B (SWI-like)
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| Chromosome |
17
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6J
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| Molecular Note |
LoxP sites were inserted surrounding exon 5.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
Mice homozygous for the Arid1b Flox allele are viable and fertile, with no reported gross phenotypic or behavioral abnormalities. When maintaining a live colony, heterozygous mice may be bred together, to wildtype mice from the colony or to C57BL/6J inbred mice. Alternatively, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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