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B6;CBA-Tg(Nkx2-1-icre/ERT2)1Kess/J
Cat. No.: CEMM-07250577
Common Name: Nkx2.1-icreERT2
Nkx2-1-cre-ERT2 mice express codon optimized iCre-ERT2 in ventral forebrain precursor cells making them useful for applications requiring tamoxifen-induced deletion of floxed sequences in these cells.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Tg(Nkx2-1-icre/ERT2)1Kess
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| Allele Name |
transgene insertion 1
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| Allele Attributes |
Recombinase-expressing; Inducible
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| Gene Symbol |
Tg(Nkx2-1-icre/ERT2)1Kess
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| Gene Name |
transgene insertion 1
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| Chromosome |
UN
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| Expressed Genes |
cre/ERT2, Cre recombinase and estrogen receptor 1 (human) fusion gene
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| MGI Accession ID | show more close |
| Site of Expression |
Cre-ERT2 expression is seen in ventral forebrain precursor cells.
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| Strain of Origin |
(C57BL/6 x CBA)F1
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| Molecular Note |
A construct was generated where a Cre/ERT2 sequence is driven by the Nkx2-1 promoter.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
B6CBAF1/J
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| Breeding Considerations |
When maintaining a live colony hemizygous mice may be bred to wildtype (non-carrier) mice from the colony or to C57BL/6J.
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For Research Use Only.
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