Online Inquiry
B6;129S6-Gt(ROSA)26Sortm3Ksvo/J
Cat. No.: CEMM-07250941
Common Name: R26-LNL-GtACR1-Fred-Kv2.1
Cre recombinase-mediated excision of a floxed neomycin cassette enables these R26-CAG-LNL-GtACR1-Fred-Kv2.1 mice to conditionally express GtACR1 (Guillardia theta anion channel rhodopsin 1) fused with Kv2.1 (Kcnb1, potassium voltage gated channel, Shab-related subfamily, member 1) soma trafficking domain and FusionRed fluorescent protein (Fred). This strain enables selective, conditional optogenetic hyperpolarization, silencing and labeling of neurons.
Inquiry
| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gt(ROSA)26Sortm3Ksvo
show more
close
|
| Allele Name |
targeted mutation 3
show more
close
|
| Allele Attributes |
Conditional ready (e.g. floxed); Reporter; Inserted expressed sequence
show more
close
|
| Gene Symbol |
Gt(ROSA)26Sor
show more
close
|
| Gene Name |
gene trap ROSA 26
show more
close
|
| Chromosome |
6
show more
close
|
| MGI Accession ID | show more close |
| Strain of Origin |
129S6/SvEvTac and C57BL/6J
show more
close
|
| Molecular Note |
The targeting construct contains: a loxP-flanked neomycin cassette and GtACR1 (Guillardia theta anion channel rhodopsin 1) fused to FusionRed fluorescent protein (Fred) and the Kcnb1 soma trafficking domain followed by WPRE and polyA.
show more
close
|
For Research Use Only.
Related Products