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STOCK Raph1tm1.1Fbg/J
Cat. No.: CEMM-07250750
Common Name: Lpdflox
Lpdflox mice possess loxP sites flanking the entire coding region of the Raph1 gene. These mice may be useful in studying actin dynamics during neurodevelopment and rectal carcinomas.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Raph1tm1.1Fbg
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| Allele Name |
targeted mutation 1.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Raph1
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| Gene Name |
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
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| Chromosome |
1
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| MGI Accession ID | show more close |
| Strain of Origin |
(C57BL/6 x 129S4/SvJae)F1
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| Molecular Note |
The targeting vector is designed to insert loxP sites flanking the entire coding region. A FRT flanked neomycin resistance (neo) cassette was inserted upstream of the 3' loxP site. Flp-mediated recombination removed the FRT flanked neo cassette.
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| HUSBANDRY | |
|---|---|
| Breeding Considerations |
When maintaining a live colony, mice homozygous for the floxed allele may be bred together.
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For Research Use Only.
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