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STOCK Olig2tm2(TVA, cre)Rth/J
Cat. No.: CEMM-07250213
In this targeted mutation strain, the mouse Olig2 (oligodendrocyte transcription factor 2) locus drives expression of cre and tva (an avian-specific retroviral receptor). This strain may be useful in studies of neurodevelopment.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Olig2tm2(TVA,cre)Rth
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| Allele Name |
targeted mutation 2
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| Allele Attributes |
Recombinase-expressing
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| Gene Symbol |
Olig2
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| Gene Name |
oligodendrocyte transcription factor 2
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| Chromosome |
16
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| Expressed Genes |
TVA, subgroup A avian leukosis virus receptor, quail; Cre, Cre recombinase, bacteriophage P1
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| MGI Accession ID | show more close |
| Site of Expression |
Cre and tva (an avian-specific retroviral receptor)are expressed in Olig2-expressing cells of the central nervous system.
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| Strain of Origin |
129
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| Molecular Note |
A cDNA encoding the avian specific retroviral receptor (TVA) followed by an IRES-Cre and neo cassette was inserted immediately downstream of the translation initiation site.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
Wild-type from the colony
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| Breeding Considerations |
When maintained as a live colony, heterozygotes may be bred. Homozygotes are not viable.
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For Research Use Only.
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