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C57BL/6-Gabra5tm2.1Uru/J
Cat. No.: CEMM-07250848
Common Name: Gabra5fl
α5fl mice possess loxP sites flanking exons 4-5 of the gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 (Gabra5) gene, making them useful for tissue specific deletion of α5-subunit containing GABAA receptors (α5-GABAARs). These floxed mice may have applications related to neurotransmission.
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| Status | Live Mouse Frozen Embryo |
| Age | 4 weeks 12 weeks Customized Age |
| Sex | Male Female |
| GENETICS | |
|---|---|
| Allele Symbol |
Gabra5tm2.1Uru
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| Allele Name |
targeted mutation 2.1
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| Allele Attributes |
Conditional ready (e.g. floxed); No functional change
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| Gene Symbol |
Gabra5
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| Gene Name |
gamma-aminobutyric acid (GABA) A receptor
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| Chromosome |
7
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| MGI Accession ID | show more close |
| Strain of Origin |
C57BL/6N
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| Molecular Note |
Exons 4 and 5 were flanked by loxP sites. The selectable markers were removed in vitro.
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| HUSBANDRY | |
|---|---|
| Suggested Controls |
C57BL/6J
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| Breeding Considerations |
When maintaining a live colony, homozygous mice may be bred together.
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| Breeding Strategy |
Heterozygote x Heterozygote
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For Research Use Only.
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